The FlowTriever is an over-the-wire system designed to:
Remove clot through both mechanical and aspiration mechanisms of action
Capture and Remove large clot burden from big vessels
Treat in a single session
Eliminate the need for thrombolytics
Eliminate ICU Stay
FlowTriever Toolkit
Triever Aspiration Catheter
The Triever Aspiration Catheters feature a highly trackable, large lumen catheter, and large bore syringe designed to rapidly extract large volumes of clot while limiting blood loss.
New T20 Curve
The Triever20 Curve™ is a fully braided large bore catheter with a customizable 260⁰ bend designed for improved navigability & torqueability for challenging anatomies such as the left PA rainbow, TA, IVC and CIT in RA.
Key Features:
- Telescopic Steerability for targeted aspiration: Customizable angled tip for precise catheter placement by telescoping through the Triever24
- 260⁰ directionality range for improved navigation: Increased utility in challenging anatomies (RA, PA, IVC, Renal Veins and upper + lower extremity DVT)
- One Price, One Patient, Many Choices: Triever20 Curve™ is included in the FlowTriever Per Procedure Pricing to use complimentarily with any FlowTriever products.
Triever24 with FLEX Technology
The Triever24 with FLEX technology provides increased flexibility through its softer durometer jacket, featuring a highly trackable, large lumen catheter, and large bore syringe designed to rapidly extract large volumes of clot while limiting blood loss.
Key Features:
- 41% More Flexible than existing Triever24 catheter*
- Superior Trackability to better navigate tortuous anatomies and smoothly deliver the catheter to the left PA and through dilated right hearts
- Effective Aspiration to enhance Whoosh™ technique aspiration for maximum clot removal
No changes to the recommended procedure steps for the improved Triever24 Aspiration Catheter!
Triever Aspiration Catheter Sizes
Available in 3 sizes:
- Triever16: 16 French
- Triever20: 20 French
- Triever24: 24 French
*The FlowTriever2 Catheter is intended for use in the peripheral vasculature only
FlowTriever Gen 1
The FlowTriever Catheter Gen 1 features three self-expanding nitinol mesh disks that are designed to engage, disrupt, and deliver clot to the Triever Aspiration Catheter for extraction.
Available in 4 sizes:
S (6-10 mm)
M (11-14 mm)
L (15-18 mm)
XL (19-25mm)
FlowTriever 2
The FlowTriever 2 catheter technology features a new disk shape designed to capture and remove wall adherent clot.
Key Features:
- Laser cut element with proximal open cell design for optimized clot clearance
- New disk shape designed to disrupt clot, improving effectiveness of aspiration
- Increased usable length (120 cm) for more distal treatment
- 52% shorter deployment length
- Versatile sizing to treat vessels 6-16 mm in diameter
*The FlowTriever2 Catheter is not indicated for the treatment of pulmonary embolism
Enabling Bloodless Thrombectomy for Pulmonary Embolism
The FlowSaver™ is designed to be used with the FlowTriever System to reduce blood loss by filtering aspirated thrombi and blood for reinfusion back to the patient, thus enabling bloodless thrombectomy for pulmonary embolism (PE) procedures.
The FlowSaver is compatible with Triever Catheters and includes a 40 micron filtration system, a clot reservoir, and a 60cc collection syringe. The accessible filtration design allows for clot examination and reservoir cleaning for more filtrations. Filtered blood can be reintroduced using a standard luer lock with the 60cc collection syringe.
Indications
The FlowTriever System is indicated for the non-surgical removal of emboli and thrombi from blood vessels
Injection, infusion and/or aspiration of contrast media and other fluids into or from a blood vessel
The FlowTriever System is intended for use in the peripheral vasculature and for the treatment of pulmonary embolism.
The Triever Catheters are intended for use in peripheral vasculature and for the treatment of pulmonary embolism
Triever Catheters are also intended for use in treating clot in transit in the right atrium
The FlowTriever2 Catheter is indicated for: the non-surgical removal of emboli and thrombi from peripheral blood vessels. Injection, infusion, and/or aspiration of contrast media and other fluids into or from a blood vessel.
The FlowTriever2 Catheter is intended for use in the peripheral vasculature.
The FlowSaver Blood Filter is used with Triever Catheters for autologous blood transfusion.
Caution: Federal (USA) law restricts this device to sale by or on the order of a physician
See Instructions for Use for complete Indications for Use, contraindications, warnings, and precautions.
Case Study
Pre FlowTriever PA-gram
Post FlowTriever PA-gram
Clot Haul
“The FlowTriever System represents a valuable new option in the interventional toolbox for effectively treating PE.” (EV Today, Mar. 2019 issue)
FlowTriever Bibliography:
| # | Publication | Publication Type |
| 1 | Weinberg AS, Dohad S, Ramzy D. et al. Clot extraction with the FlowTriever device in acute massive pulmonary embolism. J. Intensive Care Med 2016. | Case Report |
| 2 | Jaber WA, Fong PP, Weisz G, et al. Acute pulmonary embolism with an emphasis on an interventional approach. JACC 2016;67(8):991-1002. | Case Report |
| 3 | Chauhan CA, Scolieri SK, Toma C. Percutaneous pulmonary embolectomy using the FlowTriever Retrieval/Aspiration System. JVIR 2017;28(4):621-3. | Case Report |
| 4 | Tukaye DN, McDaniel M, Liberman H, et al. Percutaneous pulmonary embolus mechanical thrombectomy. JACC 2017;10(1):94-5. | Case Report |
| 5 | Engelhardt TC. Rapid removal of pulmonary emboli and subsequent reversal of right ventricular dysfunction using the FlowTriever Retrieval/Aspiration System. CathLabDigest Feb 2017;25(2). | Case Report |
| 6 | Ishola A, Ahmad US, Voelkel AJ, et al. Retrieve to relieve: Novel percutaneous thrombectomy device in selected patients with pulmonary embolism. CathLab Digest; Volume 25, Issue 5, May 2017. | Single-center Case Series |
| 7 | Nosher et al. Endovascular treatment of pulmonary embolism: Selective review of available techniques. World Journal of Radiology. December 28, 2017. | Technical Review |
| 8 | Beasley R, Marston W, Annambhotla S, Jaber WA. Emerging Tools for Lytic-Free, Single-Session Treatment of Venous Thromboembolic Disease. Insert to Endovascular Today, August 2018, Vol. 17, No. 8. | Case Report |
| 9 | Attallah A, Kado H, Novel Mechanical Thrombectomy Tools for Venous Thromboembolism. Insert to Endovascular Today, November 2018, Vol. 17, No. 11. | Case Report |
| 10 | Devcic Z and Kou W. Percutaneous pulmonary embolism thrombectomy and thrombolysis: Technical tips and tricks. Semin Intervention Radio, 2018; 35:129-135 | Technical Review |
| 11 | Basman C, Rashid U, Parmar YJ, et al. The role of percutaneous vacuum-assisted thrombectomy for intracardiac and intravascular pathology. J Card Surg. 2018;33(10):666-672. | Review |
| 12 | Improving the Risk/Benefit Profile for Managing VTE With Lytic-Free Mechanical Thrombectomy, Insert to Endovascular Today, March 2019, Vol. 18, No. 3. | Case Report |
| 13 | Avgerinos E et al. Catheter-director thrombolysis versus suction thrombectomy in the management of acute pulmonary embolism. J Vasc Surg: Venous and Lym Dis 2019; 1-6. | Clinical Study |
| 14 | Yale School of Medicine: New Treatment to Remove Clots Offers Dramatic Results, March 14, 2019 | Hospital Newsletter |
| 15 | Tu T, Toma C, Tapson VF, et al. A Prospective, Single-Arm, Multicenter Trial of Catheter-Directed Mechanical Thrombectomy for Intermediate-Risk Acute Pulmonary Embolism: The FLARE Study. JACC Cardiovasc Interv. 2019;12(9):859-869. | 510k Clinical Trial |
| 16 | Tu, Maldonado, Annambhotla: Common but complex venous cases, EVT publication, July | Case Series |
| 17 | Rivera-Lebron et al. Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism: Consensus Practice from the PERT Consortium. Clinical and Applied Thrombosis/Hemostasis (25): 1-16. June 2019. | Review |
| 18 | Wible, Buckley, Cho, Bunte, Saucier, and Borsa. Safety and Efficacy of Acute Pulmonary Embolism Treated via Large-Bore Aspiration Mechanical Thrombectomy Using the Inari FlowTriever Device. J Vasc Interv Radiol 2019; 1–6. | Retrospective Single-center Study |
| 19 | Giri, Sista, Weinberg, et al. Interventional Therapies for Acute Pulmonary Embolism: Current Status and Principles for the Development of Novel Evidence. A Scientific Statement from the American Heart Association. Circulation 2019. ; 140:00-00. | Review |
| 20 | Kishore and Dillon - Is It Time to End the Therapeutic Nihilism Toward Treating VTE in Cancer Patients? EVT October issue | Case Series |
| 21 | Nezami et al., Right Atrial and Massive Pulmonary Artery Mechanical Thrombectomy Under Echocardiography Guidance Using the FlowTriever System EJVES short reports https://doi.org/10.1016/j.ejvssr.2019.10.001 | Case Report |
| 22 | Salimnia and Qaqi A Patient With Spontaneous Pulmonary Embolism and Concomitant Deep Vein Thrombosis Treated With FlowTriever and ClotTriever Mechanical Thrombectomy VASCULAR DISEASE MANAGEMENT 2019;16(11):E161-E164. |
Case Report |
| 23 | Sharp and Attallah, Future perspectives in catheter-based treatment of pulmonary embolism European Heart Journal Supplements (2019) 21 (Supplement I), I31–I37 |
Review |